Guidelines for the in-house production of Reference Materials - Version 2

Date: 31/07/1998	Ref No: LGC/VAM/1998/040	Type: Report
Author(s): Brookman B, Walker R
Organisation/Publisher: LGC

This report is a reprint of the guidelines produced originally under the VAM 94-97 programme. The guidelines highlight the key issues that analysts should take into account when preparing reference materials in-house. These include: material selection and preparation; homogeneity and stability testing; and measurement of reference values.
More detailed information and guidance on the important points is given, and these are illustrated with a range of worked examples. The user is also provided with references to additional relevant information such as ISO guides.
The use of reference materials is becoming increasingly important in analytical quality control to help laboratories monitor their day to day performance. These guidelines provide practical advice and information to help analysts prepare their own materials more effectively.

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